Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers

PHASE4CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 31, 2011

Primary Completion Date

January 31, 2012

Study Completion Date

January 31, 2012

Conditions
Healthy
Interventions
DRUG

Placebo

The subjects will be given orally placebo twice a day for 8 days prior to the study.

DRUG

Duloxetine

The subjects will be given orally duloxetine 30mg twice a day for 8 days prior to the study.

DRUG

Venlafaxine

The subjects will be given orally venlafaxine 37,5mg twice a day for 8 days prior to the study.

Trial Locations (1)

Unknown

Department of Anaesthesiology, Intensive Care, Emergency Care and Pain Medicine, Turku University and Turku University Hospital, Turku

All Listed Sponsors
lead

Turku University Hospital

OTHER_GOV

NCT01443520 - Effect of Duloxetine and Venlafaxine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol: A Three-phase Randomized Balanced Cross-over Study in Healthy Volunteers | Biotech Hunter | Biotech Hunter