The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

March 31, 2013

Study Completion Date

August 31, 2013

Conditions
Heart FailureCardiomyopathyVentricular Dysfunction
Interventions
BIOLOGICAL

MPC Intramyocardial injection

Intramyocardial injection of 25 million mesenchymal precursor cells at the time of LVAD implantation

BIOLOGICAL

Control Solution

Injection of control solution during the LVAD implantation.

Trial Locations (11)

10032

Columbia University Medical Center, New York

10467

Montefiore Einstein Heart Center, The Bronx

19104

University of Pennsylvania, Philadelphia

21201

University of Maryland, Baltimore

27710

Duke University, Durham

32610

University of Florida, Gainsville

43210

Ohio State University, Columbus

44195

Cleveland Clinic Foundation, Cleveland

55407

Minneapolis Heart Institute Foundation, Minneapolis

75230

Baylor Research Institute, Dallas

77030

Texas Heart Institute, Houston

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Deborah Ascheim

OTHER

NCT01442129 - The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation | Biotech Hunter | Biotech Hunter