Tocilizumab for KSHV-Associated Multicentric Castleman Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

September 13, 2011

Primary Completion Date

June 6, 2018

Study Completion Date

October 5, 2020

Conditions
Castleman DiseaseMulticentric Castleman DiseaseGiant Lymph Node Hyperplasia
Interventions
DRUG

Zidovudine

Zidovudine (AZT) 600 mg orally q6 hours (every 6 hours)

DRUG

Tocilizumab

Tocilizumab 8mg/kg every 2 weeks

DRUG

Valganciclovir (VGC)

Valganciclovir (VGC) 900 mg orally q12 hours (every 12 hours) on days 1-5 of a 14-day cycle.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT01441063 - Tocilizumab for KSHV-Associated Multicentric Castleman Disease | Biotech Hunter | Biotech Hunter