99
Participants
Start Date
September 30, 2011
Primary Completion Date
December 31, 2013
Study Completion Date
December 31, 2015
Use of ologen Collagen Matrix in trabeculectomy (ologen)
Place ologen CM on the top of the loosely-sutured scleral flap under conjunctiva before suturing. It is recommended to suture the scleral flap with 1 or 2 stiches loosely for the convenience of future suture lysis and to coordinate with the tamponading effect of ologen CM to create a fluctuating scleral flap that prevents bleb wound adhesion and modulates aqueous humor outflow for ideal IOP control without leakage.
Use of Mitomycin-C (MMC) in trabeculectomy
After outlining and creating a superficial scleral flap, a cellulose sponge soaked with MMC(0.4mg/mL) is applied for up to 3 mins according to physician's routine method of application. The area treated is copiously irrigated with balanced isotonic solution. Alternatively, 15mcg of MMC may be injected intra-Tenon's at the end of the procedure. Patients receiving mitomycin will be billed as per operating room practice.
Glaucoma Associates of New York, New York
New York Eye and Ear Infirmary, New York
Wills Eye Institue, Philadelphia
Northwestern Memorial Hospital, Chicago
VoldVision-Holf Eye Clinic, Rogers
Dean McGee Eye Institue, Oklahoma City
Glaucoma Associates of Texas, Dallas
Institue of Ophthalmology and Visual Science, Newark
The New York Eye & Ear Infirmary
OTHER
Robert Ritch, MD, LLC.
OTHER
Aeon Astron Europe B.V.
INDUSTRY