Staged Phase I/II Hepatitis C Prophylactic Vaccine

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

548

Participants

Timeline

Start Date

March 6, 2012

Primary Completion Date

May 25, 2018

Study Completion Date

May 25, 2018

Conditions
Hepatitis C
Interventions
BIOLOGICAL

AdCh3NSmut1

Stages I and II: Receive AdCh3NSmut1 at 2.5 x 10\^10 total virus particles (vp)/dose, intramuscularly on day 0.

BIOLOGICAL

MVA-NSmut

Stages I and II: 1 dose of MVA-NSmut at the dosage 1.8 x10\^8 plaque forming units (pfu) intramuscularly on day 56.

OTHER

Placebo

Stages I and II: Two doses of placebo intramuscularly, 1 at day 0 and 1 at day 56.

Trial Locations (5)

87102

University of New Mexico - Truman Health Services, Albuquerque

94102

UCSF Community Research Center, San Francisco

94110

Zuckerberg San Francisco General Hospital Unit 5B, San Francisco

94102-4012

University of California San Francisco - Tenderloin Clinical Research Center, San Francisco

21205-2400

Johns Hopkins School of Public Health - Wood Clinic, Baltimore

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT01436357 - Staged Phase I/II Hepatitis C Prophylactic Vaccine | Biotech Hunter | Biotech Hunter