Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

103

Participants

Timeline

Start Date

November 30, 2011

Primary Completion Date

August 31, 2013

Study Completion Date

August 31, 2013

Conditions
MelanomaMalignant Melanoma
Interventions
DRUG

CT-011

The monoclonal antibody, CT-011 is administered intravenously at 2 dosage levels, 1.5mg/kg and 6.0 mg/kg to patients with metastatic melanoma. The study drug will be given every other week for a total of up to 27 study drug infusions for about 12 months.

Trial Locations (18)

10021

Memorial Sloan Kettering Cancer Center, New York

10029

Ruttenberg Cancer Clinic - The Mount Sinai Hospital, New York

19104

University of Pennsylvania, Philadelphia

22908

University of Virginia Health System / Human Immune Therapy Center, Charlottesville

33612

Moffitt Cancer Center Cutaneous Oncology Department, Tampa

37232

Vanderbilt University Medical Center, Nashville

52621

Chaim Sheba Medical Center, Tel Litwinsky

60611

Northwestern Memorial Hospital, Chicago

60637

The University of Chicago, Chicago

75246

Baylor Univesity Medical Center, Dallas

97213

Providence Cancer Center, Portland

06520

Yale University School of Medicine, Section of Med Onc., New Haven

02114

Mass General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

Dana Farber Cancer Institute, Boston

03756

Dartmouth Hitchcock Medical Center, Lebanon

15219-2739

University of Pittsburgh Medical Center, Pittsburgh

Unknown

Hadassah Medical Center, Jerusalem

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Medivation, Inc.

INDUSTRY