NEMO1:NEonatal Seizure Using Medication Off-patent

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2013

Conditions
Neonatal Seizures
Interventions
DRUG

Bumetanide

Bumetanide - Standard Phenobarbital plus either 0.05 mg/kg,0.1 mg/kg, 0.2 mg/kg, or 0.3 mg/kg of bumetanide as determined by the the dose escalation design Maximum dose allowed is 0.3mg/kg given up to 4 times at 12 hourly intervals (total of 1.2mg/kg).

Trial Locations (7)

Unknown

Cork University Maternity Hospital, Cork

Erasmus Universitair Medisch Centrum Rotterdam, Rotterdam

Karolinska Institutet and University Hospital, Stockholm

Uppsala University Hospital, Uppsala

Leeds General Infirmary, Leeds

University College London Hospitals NHS Foundation Trust, London

3508 AB

University Medical Centre Utrecht, Utrecht

All Listed Sponsors
collaborator

Only For Children Pharmaceuticals

INDUSTRY

collaborator

Cork University Hospital

OTHER

collaborator

UMC Utrecht

OTHER

collaborator

Helsinki University Central Hospital

OTHER

collaborator

Hôpital Necker-Enfants Malades

OTHER

collaborator

The Leeds Teaching Hospitals NHS Trust

OTHER

collaborator

Karolinska University Hospital

OTHER

collaborator

University College London Hospitals

OTHER

collaborator

Uppsala University Hospital

OTHER

collaborator

Erasmus Medical Center

OTHER

lead

Great Ormond Street Hospital for Children NHS Foundation Trust

OTHER