Ampicillin for DYT-1 Dystonia Motor Symptoms

PHASE1CompletedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

September 30, 2011

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2017

Conditions
DYT-1Dystonia
Interventions
DRUG

Ampicillin

Ampicillin will be given in capsule form. Dosage will be 2 mg daily for adults and 1 mg daily for children. One capsule will be taken each day for 28 consecutive days. After the first 28 days, there will be a 7 day 'washout' period during which no capsules are taken. Following the 'washout' period, another 28-day supply of Ampicillin will be given to the patient, to be taken in the same manner as described above.

DRUG

Sugar pill

The sugar pill will be given in capsule form. Dosage will be 2 mg daily for adults and 1 mg daily for children. One capsule will be taken each day for 28 consecutive days. After the first 28 days, there will be a 7 day 'washout' period during which no capsules are taken. Following the 'washout' period, another 28-day supply of the sugar pill will be given to the patient, to be taken in the same manner as described above.

Trial Locations (1)

32607

UF Center for Movement Disorders and Neurorestoration, Gainesville

All Listed Sponsors
collaborator

Tyler's Hope for a Dystonia Cure, Inc

UNKNOWN

lead

University of Florida

OTHER

NCT01433757 - Ampicillin for DYT-1 Dystonia Motor Symptoms | Biotech Hunter | Biotech Hunter