33
Participants
Start Date
October 31, 2011
Primary Completion Date
July 31, 2015
Study Completion Date
July 31, 2015
Pyridostigmine Bromide
15, 30, and 60 mg tabs, 1 tab every 8 hours for 10 weeks. Forced titration protocol increases dose at 2 week intervals from 15 to 30 to 60 mg as tolerated. Continue maximally tolerated dose for 4 weeks and then downtitrate at weekly intervals (60 to 30 to 15) and then discontinue.
New York University Langone Medical Center, New York
Nathan Kline Institute for Psychiatric Research
OTHER
Oklahoma State University
OTHER
National Heart, Lung, and Blood Institute (NHLBI)
NIH
NYU Langone Health
OTHER