Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD

PHASE2CompletedINTERVENTIONAL
Enrollment

158

Participants

Timeline

Start Date

August 31, 2012

Primary Completion Date

May 31, 2015

Study Completion Date

June 30, 2015

Conditions
Exudative Age-related Macular Degeneration
Interventions
DRUG

4.0 mg iSONEP

4.0 mg iSONEP given monthly intravitreously for 4 months

DRUG

0.5 mg iSONEP

0.5 mg iSONEP given monthly intravitreously for 4 months

DRUG

0.5 mg Lucentis or 1.25 mg Avastin or 2 mg Eylea

0.5 mg Lucentis or 1.25 mg Avastin or 2 mg Eylea given monthly intravitreously for 4 months

DRUG

sham injection

administered monthly for 4 months

Trial Locations (44)

11967

Island Retina, Shirley

15122

Associates in Ophthalmology, West Mifflin

20815

Retina Group of Washington, Chevy Chase

21204

Retina Specialists, Towson

22031

Retina Group of Washington, Fairfax

28210

Charlotte Eye Ear Nose & Throat Associates, Charlotte

29169

Palmetto Retina Center, West Columbia

32503

Retina Specialty Institute, Pensacola

33324

Fort Lauderdale Eye Institute, Plantation

33426

Florida Eye Microsurgical Institute, Boynton Beach

33880

Center for Retina & Macular Disease, Winter Haven

33907

Retina Health Center, Fort Myers

34994

East Florida Eye Institute, Stuart

40207

Bennett & Bloom Eye Centers, Louisville

46290

Midwest Eye Institute, Indianapolis

47150

Sagar Kenyon American Eye Institute, New Albany

48034

Retina Consultants of Michigan, Southfield

48202

Henry Ford Health System, Detroit

49202

TLC Eye Care and Laser Center, Jackson

67226

Central Plains Eye MDs, Wichita

75231

Texas Retina Associates, Dallas

78240

Medical Center Ophthalmology Associates, San Antonio

Retina Associates of South Texas, San Antonio

78550

Valley Retina Institute, Harlingen

78705

Austin Retina Associates, Austin

Retina Research Center, Austin

79606

Retina Research Institute of Texas, Abilene

84107

Rocky Mountain Retina Consultants, Salt Lake City

85014

Retina Consultants of Arizona, Phoenix

85020

Associated Retina Consultants, Phoenix

85381

Retina Consultants of Arizona, Peoria

85704

Retina Centers, P.C., Tucson

90211

Retina-Vitreous Associates Medical Group, Beverly Hills

91203

Specialty Eye Care Medical Center, Glendale

92653

Retina Associates of Orange County, Laguna Hills

92705

Orange County Retina Medical Group, Santa Ana

93003

Miramar Eye Specialists, Ventura

94040

Northern California Retina Vitreous Associates, Mountain View

95008

Retinal Diagnostic Center, Campbell

95819

Retinal Consultants Medical Group, Inc., Sacramento

96701

Retina Consultants of Hawaii, ‘Aiea

97520

Retina & Vitreous Center SO, Ashland

99204

Spokane Eye Clinical Research, Spokane

02114

Ophthalmic Consultants of Boston, Boston

All Listed Sponsors
lead

Lpath, Inc.

INDUSTRY

NCT01414153 - Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD | Biotech Hunter | Biotech Hunter