Scleroderma Treatment With Autologous Transplant (STAT) Study

PHASE2CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

September 15, 2011

Primary Completion Date

September 15, 2023

Study Completion Date

September 11, 2024

Conditions
Systemic Scleroderma
Interventions
BIOLOGICAL

Anti-Thymocyte Globulin

Given IV

PROCEDURE

Autologous Hematopoietic Stem Cell Transplantation

Undergo autologous PBSCT

DRUG

Cyclophosphamide

Given IV

BIOLOGICAL

Filgrastim

Given SC

OTHER

Laboratory Biomarker Analysis

Correlative studies

DRUG

Mycophenolate Mofetil

Given PO

PROCEDURE

Peripheral Blood Stem Cell Transplantation

Undergo autologous PBSCT

DRUG

Plerixafor

Given SC

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (12)

27710

Duke University Medical Center, Durham

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor

77030

M D Anderson Cancer Center, Houston

The University of Texas Health Science Center, Houston, Houston

80218

Colorado Blood Cancer Institute, Denver

90095

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles

91010

City of Hope Comprehensive Cancer Center, Duarte

98105

Seattle Children's Hospital, Seattle

98109

Fred Hutch/University of Washington Cancer Consortium, Seattle

80217-3364

University of Colorado, Denver

02118

Boston Medical Center, Boston

Boston University School of Medicine, Boston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Fred Hutchinson Cancer Center

OTHER

NCT01413100 - Scleroderma Treatment With Autologous Transplant (STAT) Study | Biotech Hunter | Biotech Hunter