NCT01408927View on ClinicalTrials.gov

Prevalence and Level of Thienopyridine Resistance Seen in a Contemporary Percutaneous Coronary Intervention or Coronary Artery Bypass Graft Population

UnknownOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

January 31, 2016

Study Completion Date

January 31, 2016

Conditions
Increased Drug Resistance
Interventions
OTHER

Thienopyridine resistance testing

Thienopyridine resistance will be measured by flow cytometry of vasodilator-stimulated phosphoprotein (VASP) phosphorylation, and/or VerifyNow P2Y12 assay, and/or the Chrono-Log Lumi-Aggregometer, and/or the PlaCor PRT 7000 platelet reactivity assay.

OTHER

Aspirin resistance testing

Aspirin resistance will be measured by the VerifyNow aspirin resistance assay.

OTHER

Genetic polymorphism assessment

The presence of minor alleles in selected single nucleotide polymorphisms (SNPs) as measured by the Applied Biosystems Open Array system.

Trial Locations (1)

20010

RECRUITING

Washington Hospital Center, Washington D.C.

Sponsors
All Listed Sponsors
lead

Medstar Health Research Institute

OTHER