Open Label Extension Study of Epratuzumab in Subjects With Systemic Lupus Erythematosus

PHASE3CompletedINTERVENTIONAL
Enrollment

1,250

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

February 29, 2016

Study Completion Date

February 29, 2016

Conditions
Systemic Lupus Erythematosus
Interventions
DRUG

Epratuzumab

600 mg infusions delivered weekly for a total of 4 consecutive weeks (cumulative dose 2400 mg) over eight 12-week treatment cycles

DRUG

Epratuzumab

1200 mg infusions delivered every other week for a total of 4 weeks (cumulative dose 2400 mg) over eight 12 week treatment cycles

Trial Locations (228)

Unknown

539, Birmingham

557, Little Rock

515, Hemet

544, Huntington Beach

550, La Jolla

031, Los Angeles

051, Los Angeles

089, Los Angeles

531, San Leandro

594, Thousand Oaks

558, Torrance

048, Aurora

037, Colorado Springs

532, Denver

511, Bridgeport

039, Farmington

042, Aventura

514, Brandon

090, Clearwater

092, DeBary

533, Fort Lauderdale

064, Jupiter

070, Ormond Beach

084, Palm Harbor

518, Plantation

585, Port Orange

050, Tampa

538, Tampa

087, Vero Beach

537, Atlanta

044, Duluth

590, Idaho Falls

052, Chicago

096, Indianapolis

060, Shreveport

513, Lansing

599, Lansing

047, Saint Clair Shores

575, Florissant

549, St Louis

596, Nashua

568, Freehold

593, Trenton

067, Las Cruces

551, Brooklyn

553, Great Neck

545, Manhasset

053, New York

577, Roslyn

077, Charlotte

559, Charlotte

058, Durham

075, Wilmington

061, Columbus

071, Middleburg Heights

041, Oklahoma City

076, Oklahoma City

097, Oklahoma City

547, Tulsa

032, Duncansville

093, Philadelphia

073, Pittsburgh

094, Pittsburgh

535, Charleston

598, Myrtle Beach

571, Jackson

057, Memphis

574, Amarillo

078, Austin

098, Austin

570, Austin

079, Dallas

541, Houston

563, Houston

036, Mesquite

066, San Antonio

562, San Antonio

534, Seattle

429, Camperdown

427, Clayton

430, Liverpool

425, Malvern

426, Maroochydore

106, Brussels

107, Brussels

105, Leuven

104, Liège

954, Belo Horizonte

956, Campinas

955, Goiânia

950, Juiz de Fora

453, Porto Alegre

451, Recife

450, Rio de Janeiro

952, Rio de Janeiro

452, Salvador

454, São Paulo

200, Sofia

202, Sofia

203, Sofia

204, Sofia

205, Sofia

500, London

502, Hamilton

507, Mississauga

508, Rimouski

506, St. John's

504, Toronto

218, Olomouc

216, Prague

215, Zlín

226, Tallinn

113, Lille

618, Limoges

617, Montpellier

614, Paris

116, Pessac

616, Toulouse

127, Berlin

628, Berlin

633, Berlin

625, Cologne

128, Frankfurt

126, Freiburg im Breisgau

637, Hamburg

632, Herne

626, Leipzig

634, Mainz

627, Münster

129, Plochingen

636, Roßlau

631, Zerbst

349, Shatin

712, Budapest

716, Budapest

718, Budapest

717, Debrecen

711, Szeged

715, Szeged

713, Zalaegerszeg

378, Ashkelon

376, Beersheba

375, Haifa

377, Haifa

381, Jerusalem

382, Kfar Saba

380, Rehovot

379, Tel Aviv

383, Tel Litwinsky

149, Ferrara

648, Milan

148, Padua

647, Pisa

646, Roma

147, Torino

242, Kaunas

244, Klaipėda

243, Vilnius

478, Guadalajara

976, Mexico City

982, Mexico City

480, Mérida

981, Torreón

743, Bydgoszcz

744, Częstochowa

752, Elblag

754, Elblag

746, Katowice

748, Lublin

750, Lublin

742, Poznan

747, Szczecin

751, Ustroń

749, Warsaw

263, Brasov

260, Bucharest

262, Bucharest

264, Bucharest

757, Bucharest

758, Bucharest

261, Cluj-Napoca

759, Constanța

756, Galati

761, Iași

779, Moscow

285, Petrozavodsk

284, Saint Petersburg

281, Yekaterinburg

901, Cape Town

902, Durban

903, Stellenbosch

306, Busan

303, Daegu

308, Daejeon

301, Incheon

307, Seoul

302, Suwon

161, Barcelona

661, Barcelona

164, Bilbao

660, Getafe

662, Las Palmas de Gran Canaria

162, Madrid

163, Madrid

664, Madrid

166, Málaga

165, San Cristóbal de La Laguna

177, Santander

663, Santiago de Compostela

160, Seville

659, Vigo

325, Changhua

326, Chiayi City

328, Kaohsiung City

330, Taipei

791, Donetsk

799, Ivano-Frankivsk

790, Kiev

794, Kiev

797, Kiev

792, Luhansk

793, Odesa

796, Vinnytsia

677, Birmingham

178, Brighton

182, Doncaster

179, Leeds

181, Romford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

UCB Pharma

INDUSTRY

NCT01408576 - Open Label Extension Study of Epratuzumab in Subjects With Systemic Lupus Erythematosus | Biotech Hunter | Biotech Hunter