Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV

CompletedOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

March 31, 2015

Conditions
HIV-infection
Interventions
DRUG

Angiotensin II Infusion

Angiotensin II (Bachem) will be infused at 0.3 ng/kg/min for 30 minutes, then 1.0 ng/kg/min for 30 minutes, then 3.0 ng/kg/min for 30 minutes; at baseline and at each infusion concentration, serum aldosterone will be measured. BP and heart rate will be monitored at baseline and every 2 minutes during the infusion.

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT01407237 - Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV | Biotech Hunter | Biotech Hunter