Study of Hsp90 Inhibitor AUY922 for the Treatment of Patients With Refractory Gastrointestinal Stromal Tumor

PHASE2CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

February 28, 2015

Study Completion Date

February 28, 2015

Conditions
Gastrointestinal Stromal Tumor
Interventions
DRUG

AUY922

AUY922: 70 mg/m2 IV over 60 minutes on Days 1, 8, and 15 of each cycle. Treatment cycles will be repeated every 21 days. Patients will be evaluated for response at 6 and 12 weeks and then every 9 weeks (i.e., every 3 cycles) thereafter. Patients may continue treatment until evidence of disease progression.

Trial Locations (8)

32503

Woodlands Medical Center, Pensacola

32804

Florida Hospital Cancer Institute, Orlando

33705

Florida Cancer Specialists-North, St. Petersburg

33916

Florida Cancer Specialists-South, Fort Myers

37203

Tennessee Oncology, Nashville

64132

Research Medical Center, Kansas City

68114

Nebraska Methodist Hospital, Omaha

06520

Yale School of Medicine, New Haven

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

SCRI Development Innovations, LLC

OTHER