3,000
Participants
Start Date
May 23, 2012
Primary Completion Date
November 14, 2017
Study Completion Date
November 14, 2017
Rifapentine (RPT)
"RPT dosing was be based on participants' weight:~Participants who weighed 30 kg to less than 35 kg received 300 mg once daily (administered as two 150-mg tablets).~Participants who weighed 35 kg to less than 45 kg received 450 mg once daily (administered as three 150-mg tablets).~Participants who weighed greater than 45 kg received 600 mg once daily (administered as four 150-mg tablets)."
Isoniazid (INH)
Participants received one 300-mg tablet or three 100-mg tablets of INH once daily.
Pyridoxine (Vitamin B6)
"Participants received 25 mg or 50 mg of pyridoxine, based on the current local, national, or international dosing guidelines.~Participants who received 25 mg of pyridoxine took one 25-mg tablet once daily with INH.~Participants who received 50 mg of pyridoxine took two 25-mg tablets once daily with INH."
San Miguel CRS, Lima
Soweto ACTG CRS, Johannesburg
Wits Helen Joseph Hospital CRS (Wits HJH CRS), Johannesburg
Durban International Clinical Research Site CRS, Durban
Les Centres GHESKIO Clinical Research Site (GHESKIO-INLR) CRS, Port-au-Prince
Nyu Ny Nichd Crs, New York
Thai Red Cross AIDS Research Centre (TRC-ARC) CRS, Bangkok
Bronx-Lebanon Hospital Center NICHD CRS, The Bronx
Chonburi Hosp. CRS, Chon Buri
Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS, Kericho
Hosp. Geral De Nova Igaucu Brazil NICHD CRS, Rio de Janeiro
Chapel Hill CRS, Chapel Hill
Duke University Medical Center CRS, Durham
Moi University Clinical Research Center (MUCRC) CRS, Eldoret
The University of Miami AIDS Clinical Research Unit (ACRU) CRS, Miami
Kisumu Crs, Kisumu
Henry Ford Hosp. CRS, Detroit
Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS, Chiang Mai
Northwestern University CRS, Chicago
Trinity Health and Wellness Center CRS, Dallas
Houston AIDS Research Team CRS, Houston
University of Colorado Hospital CRS, Aurora
Denver Public Health CRS, Denver
Harbor-UCLA CRS, Torrance
UCSD Antiviral Research Center CRS, San Diego
Ucsf Hiv/Aids Crs, San Francisco
University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program, La Jolla
University of Southern California CRS, Los Angeles
Boston Medical Center CRS, Boston
Cooper Univ. Hosp. CRS, Camden
New Jersey Medical School Clinical Research Center CRS, Newark
Columbia P&S CRS, New York
University of Washington AIDS CRS, Seattle
Gaborone CRS, Gaborone
Molepolole CRS, Gaborone
GHESKIO Institute of Infectious Diseases and Reproductive Health (GHESKIO - IMIS) CRS, Port-au-Prince
Malawi CRS, Lilongwe
Blantyre CRS, Blantyre
Parirenyatwa CRS, Harare
Hospital Nossa Senhora da Conceicao CRS, Porto Alegre
Univ. of Sao Paulo Brazil NICHD CRS, São Paulo
Hospital Federal dos Servidores do Estado NICHD CRS, Rio de Janeiro
Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS, Rio de Janeiro
Inst de Infectologia Emilio Ribas Sao Paulo Brazil NICHD CRS, São Paulo
Barranco CRS, Lima
National Institute of Allergy and Infectious Diseases (NIAID)
NIH