Cardiac Remote Ischemic Preconditioning Before Elective Major Vascular Surgery

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

205

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2015

Conditions
Peripheral Arterial Disease
Interventions
OTHER

Ischemic preconditioning

The RIPC protocol will consist of three cycles of the following: 5-minute inflation of a blood pressure cuff around the right upper arm to 200 mmHg (or 20 above the systolic blood pressure if baseline BP \> 200 mmHg) to allow for external compression of the brachial artery resulting in transient arm ischemia, followed by a 5-minute interval of cuff deflation to allow for reperfusion. The total duration of the protocol is 30 minutes equally divided between ischemia and reperfusion. The protocol is to be applied in the patient room the morning of the operation.

OTHER

Control

A Blood Pressure cuff inflated to 40-50 mmHg

Trial Locations (1)

55417

Minneapolis VA Medical Center, Minneapolis

All Listed Sponsors
lead

Center for Veterans Research and Education

OTHER

NCT01403337 - Cardiac Remote Ischemic Preconditioning Before Elective Major Vascular Surgery | Biotech Hunter | Biotech Hunter