205
Participants
Start Date
July 31, 2011
Primary Completion Date
September 30, 2015
Study Completion Date
September 30, 2015
Ischemic preconditioning
The RIPC protocol will consist of three cycles of the following: 5-minute inflation of a blood pressure cuff around the right upper arm to 200 mmHg (or 20 above the systolic blood pressure if baseline BP \> 200 mmHg) to allow for external compression of the brachial artery resulting in transient arm ischemia, followed by a 5-minute interval of cuff deflation to allow for reperfusion. The total duration of the protocol is 30 minutes equally divided between ischemia and reperfusion. The protocol is to be applied in the patient room the morning of the operation.
Control
A Blood Pressure cuff inflated to 40-50 mmHg
Minneapolis VA Medical Center, Minneapolis
Center for Veterans Research and Education
OTHER