262
Participants
Start Date
January 17, 2012
Primary Completion Date
June 30, 2014
Study Completion Date
June 30, 2014
Darunavir
Darunavir was administered orally once a day as two 400 mg tablets with food. When the 800 mg formulation tablet became available, it was substituted for the two 400 mg tablet.
Ritonavir
Ritonavir was administered orally together with darunavir as one 100 mg tablet once daily with food.
Tenofovir disoproxil fumarate
Tenofovir disoproxil fumarate was administered orally as one 300 mg tablet once a day.
Emtricitabine
Emtricitabine was administered orally once a day as one 200 mg capsule.
Placebo for Tenofovir disoproxil fumarate
Placebo for tenofovir disoproxil fumarate was administered orally once a day as one tablet.
Placebo for Maraviroc
Placebo for maraviroc was administered orally once a day as one tablet.
Maraviroc
Maraviroc was administered orally once a day as one 150 mg tablet.
Columbia Physicians and Surgeons CRS (30329), New York
Trillium Health ACTG CRS (1108), Rochester
University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787), Rochester
Hops. of Univ. of Pennsylvania CRS (6201), Philadelphia
Georgetown University CRS (GU CRS) (1008), Washington D.C.
Children's National Med. Ctr. ATN CRS (33003), Washington D.C.
IHV Baltimore Treatment CRS (4651), Baltimore
201 Johns Hopkins University CRS, Baltimore
Moses H. Cone Memorial Hospital CRS (3203), Greensboro
Unc Aids Crs (3201), Chapel Hill
The Ponce de Leon Center CRS (5802), Atlanta
Univ. of Miami AIDS CRS (901), Miami
Univ. of South Florida (USF) College of Medicine ATN CRS (33001), Tampa
31788 Alabama CRS, Birmingham
Vanderbilt Therapeutics CRS (3652), Nashville
St. Jude Children's Research Hosp. ATN CRS (33016), Memphis
The Ohio State Univ. AIDS CRS (2301), Columbus
Case CRS (2501), Cleveland
Metro Health CRS (2503), Cleveland
Univ. of Cincinnati CRS (2401), Cincinnati
Northwestern University CRS (2701), Chicago
Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago
Washington U CRS (2101), St Louis
Peabody Health Center CRS (31443), Dallas
Houston AIDS Research Team CRS (31473), Houston
Texas Childrens Hospital ATN CRS (33018), Houston
University of Colorado Hospital CRS (6101), Aurora
University of Colorado Denver ATN CRS (33022), Denver
UCLA CARE Center CRS (601), Los Angeles
Ucsd, Avrc Crs (701), San Diego
Ucsf Aids Crs (801), San Francisco
University of Washington AIDS CRS (1401), Seattle
University of Southern California (1201), Los Angeles
Massachusetts General Hospital ACTG CRS (101), Boston
Brigham and Women's Hosp. ACTG CRS (107), Boston
Cooper Univ. Hosp. CRS (31476), Camden
The Miriam Hospital ACTG CRS (2951), Providence
Puerto Rico-AIDS CRS (5401), San Juan
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NETWORK