The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1

PHASE4CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

December 31, 2012

Study Completion Date

December 31, 2012

Conditions
Pharmacogenetics of Metformin
Interventions
DRUG

Metformin

The study was designed as a randomized, cross-over trial with a washout period of at least 4 weeks between the phases. In both phases, the volunteers fasted for 42 h. This was done in order to include an evaluation of the pharmacodynamic effect of metformin on the glucose production in fasting healthy volunteers.

Trial Locations (1)

5000

Clinical pharmacology, Institute og public health, University of Southern Denmark, Odense

All Listed Sponsors
collaborator

Region of Southern Denmark

OTHER

lead

University of Southern Denmark

OTHER

NCT01400191 - The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1 | Biotech Hunter | Biotech Hunter