57
Participants
Start Date
July 31, 2011
Primary Completion Date
December 28, 2020
Study Completion Date
December 28, 2020
everolimus and bevacizumab
Cycle length will be defined as 28 days. Treatment will include everolimus 10mg, self administered orally once daily on a continuous schedule (days 1-28), and bevacizumab 10mg/kg, administered intravenously on days 1 and 15 of each cycle. Treatment will be continued until disease progression, major toxicity, or withdrawal from the study for any reason. Dose modification will be permitted based on toxicity. Patients that come off study before 6 months before documented progression/death will be treated as events for the 6 month PFS endpoint.
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Westchester, Harrison
Memorial Sloan Kettering Cancer Center @ Suffolk, Commack
Memorial Sloan Kettering at Basking Ridge, Basking Ridge
Memorial Sloan Kettering Cancer Center at Basking Ridge, Basking Ridge
Memorial Sloan Kettering Monmouth, Middletown
Memorial Sloan Kettering at Mercy Medical Center, Rockville Centre
Collaborators (1)
Novartis Pharmaceuticals
INDUSTRY
Memorial Sloan Kettering Cancer Center
OTHER