Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX

PHASE2CompletedINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

November 30, 2018

Study Completion Date

March 31, 2019

Conditions
Metastatic or Recurrent Gastric AdenocarcinomaHer-2 Positive Gastric Cancer
Interventions
DRUG

Herceptin+XELOX

"Each 3-weekly cycle, with chemotherapy given for 6 cycles, and trastuzumab continued even after completion of the combination chemotherapy until disease progression~* Trastuzumab: 8 mg/kg i.v. loading dose on day 1, followed by 6 mg/kg i.v.infusion every 3 weeks~* Capecitabine: 1000 mg/m2 oral twice daily for 14 days every 3 weeks (from evening on day 1 to morning on day 15)~* Oxaliplatin 130 mg/m2 i.v. on day 1"

Trial Locations (1)

Unknown

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Asan Medical Center

OTHER

NCT01396707 - Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX | Biotech Hunter | Biotech Hunter