Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of Oxycodone

PHASE2CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

August 31, 2010

Primary Completion Date

January 31, 2014

Study Completion Date

April 30, 2014

Conditions
Opioid Abuse
Interventions
DRUG

pioglitazone

A PPARγ agonist, also marketed as Actos. Participants will be maintained on ascending doses of Placebo, pioglitazone 15 mg and 45 mg, prior to completing a lab session at the end of each dosing period.

Trial Locations (1)

10032

Columbia Univ/ NYSPI Division on Substance Abuse, New York

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Omeros Corporation

INDUSTRY

lead

New York State Psychiatric Institute

OTHER