92
Participants
Start Date
September 30, 2011
Primary Completion Date
February 28, 2014
Study Completion Date
February 28, 2014
inhaled nitric oxide
Study drug will be administered using an INOpulse delivery system that delivers small pulses of study drug to the patient via a nasal cannula. Subjects randomized to the intervention arm will receive a dose equivalent to 80 ppm iNO in air for 24 hours per day for a minimum of two days and until clinical improvement (coma recovery), death or a maximum of 5 days.
Placebo
The placebo will be administered using an INOpulse delivery system that delivers small pulses of study drug to the patient via a nasal cannula. Subjects randomized to the placebo arm will receive nitrogen in air for 24 hours per day for a minimum of two days and until clinical improvement (coma recovery), death or a maximum of 5 days.
Mbarara Regional Referral Hospital, Mbarara
Lead Sponsor
Mbarara University of Science and Technology
OTHER
Massachusetts General Hospital
OTHER
Harvard Medical School (HMS and HSDM)
OTHER
Medecins Sans Frontieres, Netherlands
OTHER
Epicentre
OTHER