NCT01387594 - Evaluate PF-00547659 On Cerebrospinal Fluid Lymphocytes In Volunteers With Crohn's Disease Or Ulcerative Colitis Who Failed Or Did Not Tolerate Anti-TNFs | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 3, 2012

Primary Completion Date

March 31, 2014

Study Completion Date

November 26, 2015

Conditions

Crohn's DiseaseIleitisIleo-colonic and Colonic Crohn's DiseaseGranulomatous ColitisRegional EnteritisUlcerative Colitis

Interventions

PROCEDURE

lumbar puncture

2 lumbar punctures prior to treatment; study drug 225mg SC once a month X 3 doses.

DRUG

lumbar puncture

1 lumbar puncture before and after 3 doses; study drug 225mg SC once a month X 3 doses.

Trial Locations (9)

AKH Wien Universitaetsklinik fuer Innere Medizin III Klinische Abteilung fuer Gastroenterologie und, Vienna

Charité, Universitaetsmedizin Berlin, Campus Virchow Klinikum,, Berlin

Hopital Cardiologique, Lille

Hopital Huriez, CHRU de Lille, Lille

Hopital Saint-Louis - CIC, Paris

Hopital Saint-Louis, Paris

Hopital Erasme, Brussels

UZ Gasthuisberg, Leuven

Academic Medical Center - University of Amsterdam, Dept. of Gastroenterology, Amsterdam