Effect of Adalimumab for the Treatment of Uveitis in Juvenile Idiopathic Arthritis

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

June 29, 2011

Primary Completion Date

November 4, 2014

Study Completion Date

August 27, 2015

Conditions
UveitisJuvenile Arthritis
Interventions
DRUG

Anti-tumor necrosis factor alpha monoclonal antibody

The dose of adalimumab will be 40 mg for children age 13 and over and for children younger than 13 adalimumab 24 mg per m2 BSA (up to a maximum total body dose of 40 mg).

DRUG

placebo

Patients will receive 4 injections of placebo on D0, D14, D28, and D42 with assessment of the primary endpoint at M2

Trial Locations (1)

75015

Hospital of necker Enfants malades, Paris

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Abbott

INDUSTRY

collaborator

URC-CIC Paris Descartes Necker Cochin

OTHER

lead

Assistance Publique - Hôpitaux de Paris

OTHER