Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

May 31, 2015

Study Completion Date

May 31, 2015

Conditions
Aging
Interventions
DRUG

N-acetylcysteine

50 mg/kg/dose. 3 total doses: 1 dose on day 1, 2 doses on day 2.

DRUG

Losartan

25mg/dose. 3 total doses: 1 dose on day 1, 2 doses on day 2.

DRUG

Placebo losartan

Placebo losartan 3 total doses: 1 dose on day 1, 2 doses on day 2.

DRUG

Placebo N-acetylcysteine

Placebo N-acetylcysteine 3 total doses: 1 dose on day 1, 2 doses on day 2.

Trial Locations (1)

77555

University of Texas Medical Branch, Galveston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Lantheus Medical Imaging

INDUSTRY

lead

The University of Texas Medical Branch, Galveston

OTHER

NCT01384591 - Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly | Biotech Hunter | Biotech Hunter