Safety Study of ²¹²Pb-TCMC-Trastuzumab Radio Immunotherapy

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

October 31, 2015

Study Completion Date

July 31, 2016

Conditions
Breast NeoplasmsPeritoneal NeoplasmsOvarian NeoplasmsPancreatic NeoplasmsStomach Neoplasms
Interventions
OTHER

²¹²Pb-TCMC-Trastuzumab

The starting dose level will be 200 μCi/m² of ²¹²Pb-TCMC-Trastuzumab. Three to six patients will be treated at each dose level, and dose escalation will proceed if no more than 1 out of 6 patients in a cohort experiences dose limiting toxicity. Six patients will be treated at the maximum tolerated dose.

BIOLOGICAL

trastuzumab

4 mg/kg.

Trial Locations (2)

35233

University Of Alabama at Birmingham, Birmingham

Unknown

UCSD Moores Cancer Center, San Diego

All Listed Sponsors
lead

Orano Med LLC

INDUSTRY

NCT01384253 - Safety Study of ²¹²Pb-TCMC-Trastuzumab Radio Immunotherapy | Biotech Hunter | Biotech Hunter