MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

PHASE1CompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

September 30, 2011

Primary Completion Date

July 31, 2014

Study Completion Date

November 30, 2014

Conditions
Multiple Myeloma
Interventions
BIOLOGICAL

recMAGE-A3 Protein + AS15 Adjuvant

recMAGE-A3 + AS15 was administered intramuscularly at a dose of 300 µg recMAGE-A3, with no dose adjustments permitted. The first immunization was administered 6 to 15 week prior to auto-SCT, with subsequent immunizations administered on Days 10, 31, 52, 73, and 94 (± 3 days) and Days 180 and 270 (± 7 days) after auto-SCT.

Trial Locations (4)

10016

New York University School of Medicine, New York

10029

Mount Sinai Hospital, New York

10065

Memorial Sloan-Kettering Cancer Center, New York

19111

Fox Chase Cancer Center, Philadelphia

Sponsors
All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

collaborator

MOUNT SINAI HOSPITAL

OTHER

collaborator

NYU Langone Health

OTHER

collaborator

Fox Chase Cancer Center

OTHER

collaborator

Memorial Sloan Kettering Cancer Center

OTHER

lead

Ludwig Institute for Cancer Research

OTHER