A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension

PHASE2CompletedINTERVENTIONAL
Enrollment

282

Participants

Timeline

Start Date

January 31, 2003

Primary Completion Date

March 31, 2003

Study Completion Date

April 30, 2003

Conditions
Primary Open Angle GlaucomaOcular Hypertension
Interventions
DRUG

latanoprost 75 ug

"Eligible patients were randomized to receive 1 of 4 different doses of latanoprost (50, 75, 100 or 125 ug/mL).~Study medication was supplied in clear bottles. Patients were instructed to instill one drop of study medication in one or both eyes (as instructed by their investigator) once daily in the evening between 7 PM and 9 PM during the entire treatment period. The first dose of study medication was instilled in the evening of the baseline visit and the last dose was instilled in the evening before the Week 4 (Day 28) visit."

DRUG

latanoprost 100 ug

"Eligible patients were randomized to receive 1 of 4 different doses of latanoprost (50, 75, 100 or 125 ug/mL).~Study medication was supplied in clear bottles. Patients were instructed to instill one drop of study medication in one or both eyes (as instructed by their investigator) once daily in the evening between 7 PM and 9 PM during the entire treatment period. The first dose of study medication was instilled in the evening of the baseline visit and the last dose was instilled in the evening before the Week 4 (Day 28) visit."

DRUG

latanoprost 125 ug

"Eligible patients were randomized to receive 1 of 4 different doses of latanoprost (50, 75, 100 or 125 ug/mL).~Study medication was supplied in clear bottles. Patients were instructed to instill one drop of study medication in one or both eyes (as instructed by their investigator) once daily in the evening between 7 PM and 9 PM during the entire treatment period. The first dose of study medication was instilled in the evening of the baseline visit and the last dose was instilled in the evening before the Week 4 (Day 28) visit."

DRUG

latanoprost 50 ug

"Eligible patients were randomized to receive 1 of 4 different doses of latanoprost (50, 75, 100 or 125 ug/mL).~Study medication was supplied in clear bottles. Patients were instructed to instill one drop of study medication in one or both eyes (as instructed by their investigator) once daily in the evening between 7 PM and 9 PM during the entire treatment period. The first dose of study medication was instilled in the evening of the baseline visit and the last dose was instilled in the evening before the Week 4 (Day 28) visit."

Trial Locations (25)

2000

Eye Associates Pty Limited, Sydney

Save Sight Institute, Sydney

3000

A.I.B.I.L.I., Coimbra

5000

Royal Adelaide Hospital, North Terrace, Adelaide

10700

Siriraj Hospital, Ophthalmology, Bangkok

75016

Fondation Adolphe De Rothchild, Paris

CZ - 62500

University Hospital Brno-Bohunice, Brno

120 00

Specializovana Glaukomova Poradna, Blanicka 25, Prague

128 21

VseobecnBfakultnf nemocnice, Prague

150 00

Private Ophthalmology, V Hurkach 1296, Prague

160 60

Institute of Aviation Medicine, Generalal Piky 1, Prague

Unknown

Hopital De La Timone, Marseille

Hopital Des Armees Laveran, Marseille

Hopital Civil, Strasbourg

Akadimos Ophthalmology Center of Northern Greece, Thessaloniki

Layton Rahmatullah Benevolent Trust (LRBT), Eye Hospital, Lahore

Services Hospital Lahore, Lahore

Aga Khan University Hospital Karachi, Karachi

Civil Hospital Karachi, Karachi

Hospital De S. Jose, Lisbon

Hospital Pedro Hispano, Matosinhos Municipality

Chulalongkorn Hospital, Bangkok

B9 5SS

Birmingham Heartlands Hospital, Birmingham

G4 0SF

Glasgow Royal Infirmary, Glasgow

SR2 9HP

Sunderland Eye Infirmary, Sunderland

All Listed Sponsors
lead

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

INDUSTRY

NCT01379144 - A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The Treatment Of Primary Open-Angle Glaucoma And Ocular Hypertension | Biotech Hunter | Biotech Hunter