Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
Mild Intermittent Asthma (Gina 1)
Interventions
OTHER

Bronchoscopy

"In brief, during the first bronchoscopy a baseline BAL and baseline endobronchial brush and forceps biopsies will be obtained and allergen as well as saline (control segment) will be instilled.~The subjects will undergo a second bronchoscopy in order to obtain BAL from the allergen challenged segments and the saline challenged segment, and endobronchial forceps biopsies."

Trial Locations (1)

30625

Fraunhofer ITEM, Hanover

All Listed Sponsors
collaborator

Hannover Medical School

OTHER

lead

Fraunhofer-Institute of Toxicology and Experimental Medicine

OTHER

NCT01378624 - Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging | Biotech Hunter | Biotech Hunter