A Phase 3 Study of Amifampridine Phosphate in Patients With Lambert Eaton Myasthenic Syndrome (LEMS)

PHASE3CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions
Lambert Eaton Myasthenic Syndrome
Interventions
DRUG

Amifampridine Phosphate

Amifampridine, 30-80 mg given 3-4 times per day with a maximum single dose of 20 mg (2 x 10 mg tablets), for 2 weeks.

DRUG

Placebo

Matching placebo tablets administered 3-4 times a day (to the individual patient's tablet count of active at baseline) over 2 weeks.

Trial Locations (14)

10032

New York

11000

Belgrade

28007

Madrid

35233

Birmingham

66160

Kansas City

69677

Lyon

85258

Scottsdale

90095

Los Angeles

94305

Palo Alto

125367

Moscow

D-80336

Munich

D-10117

Berlin

H-7623

Pécs

02 097

Warsaw

Sponsors
All Listed Sponsors
lead

Catalyst Pharmaceuticals, Inc.

INDUSTRY

NCT01377922 - A Phase 3 Study of Amifampridine Phosphate in Patients With Lambert Eaton Myasthenic Syndrome (LEMS) | Biotech Hunter | Biotech Hunter