150
Participants
Start Date
June 30, 2011
Primary Completion Date
December 31, 2017
Study Completion Date
December 31, 2017
oral naltrexone
Following detoxification with buprenorphine (one dy of 8 mg) followed by oral naltrexone (ascending taper to 25 mg), participants will receive Vivitrol injection on Day 8. Behavioral therapy sessions will be offered for five weeks.
Buprenorphine
Following detoxification with buprenorphine \[8-mg buprenorphine (Day 1) tapering to 0 mg (Day 7)\] participants will receive Vivitrol injection on Day 15. Behavioral therapy sessions will be offered for five weeks.
Vivitrol
dose of long-acting injectable naltrexone (Vivitrol 380 mg i.m. Injection)
Substance Treatment and Research Service (STARS), Columbia University, New York
National Institute on Drug Abuse (NIDA)
NIH
New York State Psychiatric Institute
OTHER