PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

May 25, 2012

Primary Completion Date

October 28, 2019

Study Completion Date

October 28, 2019

Conditions
Chronic Hepatitis B
Interventions
DRUG

Peginterferon alfa-2a

180 μg per week s.c. for a total duration of 48 weeks.

DRUG

Nucleos(t)ide analogue

All patients are all currently being treated with long-term NA treatment and will continue using these during the study. Dosage depends on which Nucleos(t)ide analogue they are using.

Trial Locations (8)

M5G 2C4

Toronto General Hospital, Toronto

3015 CE

Erasmus Medical Center, Rotterdam

Unknown

Onze Lieve Vrouwen Gasthuis, Amsterdam

VU university medical center, Amsterdam

Rijnstate Hospital, Arnhem

Reinier de Graaf Gasthuis, Delft

Spaarne Gasthuis, Haarlem

University Medical Center Utrecht, Utrecht

Sponsors
All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Foundation for Liver Research

OTHER