Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

PHASE3CompletedINTERVENTIONAL
Enrollment

624

Participants

Timeline

Start Date

September 30, 2011

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2017

Conditions
Acute Leukemias of Ambiguous LineageBacterial InfectionDiarrheaFungal InfectionMusculoskeletal ComplicationsNeutropeniaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Myeloid LeukemiaSecondary Acute Myeloid LeukemiaUntreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions
DRUG

levofloxacin

Given PO or IV

Trial Locations (84)

10016

New York University Langone Medical Center, New York

10032

Columbia University Medical Center, New York

10595

Ny Cancer%, Valhalla

14263

Roswell Park Cancer Institute, Buffalo

14642

University of Rochester, Rochester

15224

Children's Hospital of Pittsburgh of UPMC, Pittsburgh

18017

Lehigh Valley Hospital - Muhlenberg, Bethlehem

19104

Children's Hospital of Philadelphia, Philadelphia

19803

Alfred I duPont Hospital for Children, Wilmington

20010

Children's National Medical Center, Washington D.C.

20057

Lombardi Comprehensive Cancer Center at Georgetown University, Washington D.C.

21215

Sinai Hospital of Baltimore, Baltimore

23507

Childrens Hospital-King's Daughters, Norfolk

27157

Wake Forest University Health Sciences, Winston-Salem

28801

Mission Hospital-Memorial Campus, Asheville

29203

Palmetto Health Richland, Columbia

30322

Children's Healthcare of Atlanta - Egleston, Atlanta

30912

Georgia Regents University, Augusta

32504

Nemours Children's Clinic - Pensacola, Pensacola

32827

Nemours Children's Hospital, Orlando

33407

Saint Mary's Hospital, West Palm Beach

33701

All Children's Hospital, St. Petersburg

33908

Golisano Children's Hospital of Southwest Florida, Fort Myers

39216

University of Mississippi Medical Center, Jackson

40202

Kosair Children's Hospital, Louisville

40536

University of Kentucky, Lexington

43205

Nationwide Children's Hospital, Columbus

43606

The Toledo Hospital/Toledo Children's Hospital, Toledo

44195

Cleveland Clinic Foundation, Cleveland

44308

Children's Hospital Medical Center of Akron, Akron

45404

The Children's Medical Center of Dayton, Dayton

46202

Riley Hospital for Children, Indianapolis

46260

Saint Vincent Hospital and Health Services, Indianapolis

48109

C S Mott Children's Hospital, Ann Arbor

48910

Michigan State University - Breslin Cancer Center, Lansing

49503

Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids

50309

Blank Children's Hospital, Des Moines

54449

Marshfield Clinic, Marshfield

55404

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis

60453

Advocate Children's Hospital-Oak Lawn, Oak Lawn

60612

University of Illinois, Chicago

63141

Saint John's Mercy Medical Center, St Louis

68114

Children's Hospital and Medical Center of Omaha, Omaha

68198

University of Nebraska Medical Center, Omaha

70112

Tulane University Health Sciences Center, New Orleans

70118

Children's Hospital-Main Campus, New Orleans

70121

Ochsner Medical Center, New Orleans

73104

University of Oklahoma Health Sciences Center, Oklahoma City

75390

University of Texas Southwestern Medical Center, Dallas

76104

Cook Children's Medical Center, Fort Worth

77030

Baylor College of Medicine, Houston

78229

Methodist Children's Hospital of South Texas, San Antonio

78234

Brooke Army Medical Center, Fort Sam Houston

78411

Driscoll Children's Hospital, Corpus Christi

87106

University of New Mexico Cancer Center, Albuquerque

89106

Nevada Cancer Research Foundation CCOP, Las Vegas

90027

Children's Hospital Los Angeles, Los Angeles

90048

Cedars-Sinai Medical Center, Los Angeles

90242

Southern California Permanente Medical Group, Downey

90806

Miller Children's Hospital, Long Beach

91010

City of Hope Medical Center, Duarte

92123

Rady Children's Hospital - San Diego, San Diego

92354

Loma Linda University Medical Center, Loma Linda

94143

University of California San Francisco Medical Center-Parnassus, San Francisco

98431

Madigan Army Medical Center, Tacoma

99204

Providence Sacred Heart Medical Center and Children's Hospital, Spokane

72202-3591

Arkansas Children's Hospital, Little Rock

06106

Connecticut Children's Medical Center, Hartford

32207-8426

Nemours Children's Clinic - Jacksonville, Jacksonville

02111

Floating Hospital for Children at Tufts Medical Center, Boston

02115

Dana-Farber Cancer Institute, Boston

07601

Hackensack University Medical Center, Hackensack

08901

Saint Peter's University Hospital, New Brunswick

08903

UMDNJ - Robert Wood Johnson University Hospital, New Brunswick

10467-2490

Montefiore Medical Center, The Bronx

17822-2001

Geisinger Medical Center, Danville

57117-5134

Sanford USD Medical Center - Sioux Falls, Sioux Falls

78229-3900

University of Texas Health Science Center at San Antonio, San Antonio

R3E 0V9

CancerCare Manitoba, Winnipeg

A1B 3V6

Janeway Child Health Centre, St. John's

L8N 3Z5

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton

K7L 5P9

Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston

M5G 1X8

Hospital for Sick Children, Toronto

H3H 1P3

The Montreal Children's Hospital of the MUHC, Montreal

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT01371656 - Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation | Biotech Hunter | Biotech Hunter