Clinical Diagnosis of Basal Cell Carcinoma Subtype

CompletedOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

February 28, 2013

Study Completion Date

February 28, 2013

Conditions
Basal Cell Carcinoma
Interventions
PROCEDURE

Punch biopsy

Punch biopsy is a 10 minutes treatment at the outpatient department of dermatology. Patient will lie down on a bed, the skin will be disinfected and local anaesthesia (lidocaine 1% with epinephrine) will be given, which is briefly painful. Then a PB of 3 mm is taken from the most suspected area. In the case of continuing bleeding the wound will be sutured. A properly taken biopsy will leave no or minimal scarring, but this is not relevant since a SE will be performed afterwards. In very rare cases post-biopsy bleeding or infection occurs.

PROCEDURE

Surgical excision

"Surgical excision takes place in 30 minutes. Patient will lie down on a bed, the skin will be disinfected and local anaesthesia will be given. sBCC and nBCC will be excised with a 3 mm margin, aBCC with a 5 mm margin. Most BCC can be surgically excised, but some have to be treated with Mohs micrographic surgery (MMS). MMS ensures total BCC removal, preserving as much surrounding skin with 100% margin control. All BCCs will be excised with a 2 mm margin and examined under the microscope. This will totally take 1.5-2.0 hours. If tumour is still present, another tissue layer with 2 mm margin will be excised. It usually takes removal of 1-3 tissue layers to complete MMS.~After both treatments, wounds will be sutured and removed after 1-2 weeks, depending on the localisation. Within the first two weeks posttreatment, patients have to avoid physical heavy movements and keep the suture dry. Possible complications: scarring, continuous or subsequent bleeding, infection and dehiscent wounds."

Trial Locations (2)

6202 AZ

Maastricht University Medical Center, Maastricht

Unknown

Erasmus Medical Centre Rotterdam, Rotterdam

All Listed Sponsors
lead

Maastricht University Medical Center

OTHER

NCT01370824 - Clinical Diagnosis of Basal Cell Carcinoma Subtype | Biotech Hunter | Biotech Hunter