Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

February 29, 2012

Primary Completion Date

March 31, 2016

Study Completion Date

March 31, 2016

Conditions
Chemotherapy-induced Nausea and Vomiting
Interventions
DRUG

Palonosetron

Prior to IV chemotherapy - ondansetron 8mg IV \& Dexamethasone 10 mg IV On the last day of chemotherapy - Palonosetron .25 mg IV, dexamethasone 10mg IV Day 1-2 after IV chemotherapy - Dexamethasone 8 mg PO

DRUG

ondansetron

Prior to IV chemotherapy - ondansetron 8mg IV \& Dexamethasone 10 mg IV On the last day of chemotherapy - Palonosetron .25 mg IV, dexamethasone 10mg IV

DRUG

Dexamethasone

Prior to IV chemotherapy - ondansetron 8mg IV \& Dexamethasone 10 mg IV On the last day of chemotherapy - Palonosetron .25 mg IV, dexamethasone 10mg IV

Trial Locations (1)

30342

Northside Hospital, Atlanta

All Listed Sponsors
collaborator

Blood and Marrow Transplant Group of Georgia

OTHER

lead

Northside Hospital, Inc.

OTHER

NCT01370408 - Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients | Biotech Hunter | Biotech Hunter