Entecavir/Pegylated Interferon in Immune Tolerant Children With Chronic Hepatitis B Virus (HBV) Infection

PHASE3CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 30, 2012

Primary Completion Date

December 23, 2016

Study Completion Date

December 23, 2016

Conditions
Hepatitis B
Interventions
DRUG

Entecavir and peginterferon

Entecavir 0.015 mg/kg/day (up to 0.5 mg maximum daily dose) once daily for 48 weeks and Peginterferon alfa-2a 180 µg/1.73m2 subcutaneously once weekly for 40 weeks beginning 8 weeks after entecavir monotherapy).

Trial Locations (7)

21287

Johns Hopkins University, Baltimore

55455

University of Minnesota, Minneapolis

63104

Saint Louis Children's Medical Center, St Louis

75235

University of Texas Southwestern, Dallas

94143

University of California San Francisco Medical Center, San Francisco

98015

Seattle Children's Hospital, Seattle

m5g1x8

Hospital of Sick Children, Toronto

All Listed Sponsors
lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

NCT01368497 - Entecavir/Pegylated Interferon in Immune Tolerant Children With Chronic Hepatitis B Virus (HBV) Infection | Biotech Hunter | Biotech Hunter