NCT01364883 - Safety and Immunogenicity of Novel Vaccination Schedules With Malaria Vaccines AdCh63 ME-TRAP and MVA ME-TRAP | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2011

Primary Completion Date

July 31, 2013

Study Completion Date

July 31, 2013

Conditions

Malaria

Interventions

BIOLOGICAL

Vaccination Schedule One

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Two

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Three

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Four

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Five

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Six

Intramuscular injection of 5x10\^10 vp of AdCh63 ME-TRAP, intramuscular injection of 2x10\^8 pfu of MVA ME-TRAP

BIOLOGICAL

Vaccination Schedule Seven

AdCh63 ME-TRAP prime D0, AdCh63 ME-TRAP boost W8, AdCh63 ME-TRAP boost W16, MVA ME-TRAP boost W24

Trial Locations (1)

Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford

All Listed Sponsors

lead

University of Oxford

OTHER