Tolerability, Safety and Pharmacokinetics of Four Formulations of Ketorolac Tromethamine in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

August 31, 2005

Primary Completion Date

September 30, 2005

Study Completion Date

March 31, 2006

Conditions
Healthy Volunteers
Interventions
DRUG

Ketorolac Tromethamine

30 mg Ketorolac Tromethamine intranasal (IN)

DRUG

Ketorolac Tromethamine with 4% Lidocaine hydrochloride (HCl)

30 mg Ketorolac Tromethamine with 4% Lidocaine HCl IN

DRUG

Ketorolac Tromethamine with 5% Lidocaine HCl

30 mg Ketorolac Tromethamine with 5% Lidocaine HCl IN

DRUG

30 mg Ketorolac Tromethamine with 6% Lidocaine HCl

30 mg Ketorolac Tromethamine with 6% Lidocaine HCl IN

Trial Locations (1)

Unknown

Medeval Ltd, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Egalet Ltd

INDUSTRY