Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

June 30, 2011

Primary Completion Date

September 30, 2011

Study Completion Date

September 30, 2011

Conditions

Healthy VolunteersRheumatoid Arthritis

Interventions

DRUG

Digoxin

oral tablets, 0.25mg bd on Day 1 and 0.25 Once daily from Day 2 to 15

DRUG

Fostamatinib

oral tablets, 100mg (2 X 50mg) bd from Day 9 - 15

Trial Locations (1)

Research Site, London