Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

November 30, 2013

Study Completion Date

January 31, 2014

Conditions
Cancer
Interventions
DRUG

AMP-224

Escalating doses of AMP-224

DRUG

AMP-224

Stage 2 will further explore the safety, pharmacokinetics, and preliminary clinical activity of AMP-224 in at least one tumor type based on pharmacodynamic assessments and clinical activity emerging from the Dose-Escalation Phase. Tumor tissue and blood

Trial Locations (4)

10065

Memorial Sloan Kettering Cancer Center, New York

28078

Carolina BioOncology Institute, Huntersville

37203

Sarah Cannon Research Institute, Nashville

48201

Karmanos Cancer Institute, Detroit

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

MedImmune LLC

INDUSTRY