515
Participants
Start Date
March 13, 2012
Primary Completion Date
October 29, 2014
Study Completion Date
October 29, 2014
Lopinavir/ritonavir
Lopinavir 400mg/ritonavir 100mg (given as two LPV 200mg/RTV 50mg fixed-dose combination tablets) orally twice daily, with or without food, throughout follow-up.
Lopinavir/ritonavir
Lopinavir 400mg/ritonavir 100mg (given as three LPV 133.3 mg/RTV 33.3 mg fixed-dose combination soft gelatin capsules) orally twice daily, with food, throughout follow-up.
Raltegravir
Raltegravir 400 mg tablet orally twice daily, with or without food, throughout follow-up.
Emtricitabine/tenofovir disoproxil fumarate
Emtricitabine 200 mg/tenofovir disoproxil fumarate 300mg fixed-dose combination tablet orally once daily, with or without food, throughout follow-up.
Abacavir/lamivudine/zidovudine
Abacavir 300 mg/lamivudine 150 mg/zidovudine 300 mg fixed-dose combination tablet orally twice daily, with or without food, throughout follow-up.
Abacavir/lamivudine
Abacavir 600 mg/lamivudine 300 mg fixed-dose combination tablet orally once daily, with or without food, throughout follow-up.
Lamivudine/zidovudine
Lamivudine 150 mg/zidovudine 300 mg fixed-dose combination tablet orally twice daily, with or without food, throughout follow-up.
Abacavir
Abacavir 300 mg tablet orally twice daily or 600 mg (given as two 300 mg tablets) once daily, with or without food, throughout follow-up.
Zidovudine
Zidovudine 300 mg tablet orally twice daily, with or without food, throughout follow-up.
Lamivudine
Lamivudine 150 mg tablet orally twice daily, with or without food, throughout follow-up.
Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro
AMPATH at Moi Univ. Teaching Hosp. Eldoret CRS (12601), Eldoret
Chiang Mai University ACTG CRS (11501), Chiang Mai
BJ Medical College CRS (31441), Pune
NARI Pune CRS, Pune
Y.R.G Ctr, for AIDS Research and Education (11701), Chennai
College of Med. JHU CRS (30301), Blantyre
University of North Carolina Lilongwe CRS (12001), Lilongwe
San Miguel CRS, San Miguel
Wits HIV CRS (11101), Johannesburg
Soweto ACTG CRS (12301), Johannesburg
Univ. of Witwatersrand CRS (11101), Johannesburg
Kilimanjaro Christian Medical CRS, Kilimanjaro Region
UZ-Parirenyatwa CRS (30313), Harare
Barranco CRS (11301), Lima
Durban Adult HIV CRS (11201), Durban
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NETWORK