Investigational Drug in Combination With Two Chemotherapy Drugs in Women With Locally Recurrent or Metastatic Breast Cancer

PHASE1/PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2013

Primary Completion Date

September 30, 2015

Study Completion Date

September 30, 2018

Conditions
Breast CancerMetastatic Breast CancerStage IV Breast Cancer
Interventions
DRUG

Ixabepilone

Patients will receive ixabepilone at 40 mg/m2.

DRUG

Capecitabine

Patients will receive capecitabine at 2000 mg/m2.

DRUG

Motesanib

Patient will receive motesanib at 100mg or 125mg once daily dependent on outcome of Phase I, which will involve the first 3-6 patients.

Trial Locations (1)

19107

Thomas Jefferson University, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Susan G. Komen Breast Cancer Foundation

OTHER

collaborator

Amgen

INDUSTRY

lead

Sidney Kimmel Cancer Center at Thomas Jefferson University

OTHER