Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 21, 2011

Primary Completion Date

January 20, 2015

Study Completion Date

January 9, 2018

Conditions
Acute Myeloid Leukemia
Interventions
DRUG

PLX3397

Maximum Tolerated Dose of PLX3397 will be administered orally, twice daily.

DRUG

PLX3397

The drug product is available in capsule form, to be taken orally.

Trial Locations (9)

10022

Memorial Sloan Kettering Cancer Center, New York

10065

New York Presby Hospital, Weill Medical College at Cornell University, New York

14263

Roswell Park Cancer Institute, Buffalo

19104

University of Pennsylvania, Abramson Cancer Center, Philadelphia

21231

Johns Hopkins University, Baltimore

60611

Northwestern University, Chicago

94143

UCSF Helen Diller Family Family Comprehensive Cancer Center, San Francisco

98109

Fred Hutchinson Cancer Research Center, Seattle

02215

Dana Farber Cancer Institute, Boston

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Plexxikon

INDUSTRY

lead

Daiichi Sankyo

INDUSTRY