Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049)

PHASE3CompletedINTERVENTIONAL
Enrollment

705

Participants

Timeline

Start Date

November 17, 2011

Primary Completion Date

January 9, 2013

Study Completion Date

February 9, 2017

Conditions
MalariaMalaria Vaccines
Interventions
BIOLOGICAL

GlaxoSmithKline (GSK) Biologicals' candidate Plasmodium falciparum malaria vaccine 257049

Children enrolled in 9 groups will receive 3 doses of the candidate malaria vaccine (Lot 1, 2 and 3) by intramuscular injection.

BIOLOGICAL

Engerix-B™ vaccine

Children enrolled in 2 groups will receive 4 doses of Engerix-B™ vaccine by intramuscular injection. Children enrolled in all other groups will receive one dose of Engerix-B vaccine by intramuscular injection.

BIOLOGICAL

Infanrix/Hib™ vaccine

Children enrolled in all 11 groups will receive 4 doses of Infanrix/Hib™ vaccine by intramuscular injection

BIOLOGICAL

Polio Sabin™ vaccine

Children enrolled in all 11 groups will receive 3 doses of Polio Sabin™ by intramuscular injection.

BIOLOGICAL

Rotarix™ vaccine

Children enrolled in all 11 groups will receive 2 doses of oral Rotarix™ vaccine.

BIOLOGICAL

Synflorix™ vaccine

Children enrolled in all 11 groups will receive 4 doses of Synflorix™ vaccine by intramuscular injection.

BIOLOGICAL

Measles vaccine

Children enrolled in all 11 groups will receive 1 dose of measles vaccine by intramuscular injection.

BIOLOGICAL

Yellow fever vaccine

Children enrolled in all 11 groups will receive 1 dose of yellow fever vaccine by intramuscular injection.

Trial Locations (2)

Unknown

GSK Investigational Site, Ouagadougou

GSK Investigational Site, Kumasi

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY

NCT01345240 - Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) | Biotech Hunter | Biotech Hunter