160
Participants
Start Date
March 10, 2011
Primary Completion Date
June 17, 2016
Study Completion Date
October 28, 2016
IV Ganciclovir
For first 5 days, dosing of intravenous ganciclovir is 10 mg/kg daily, given as 5 mg/kg every 12 hours (adjusted for renal function). After first 5 days (up to 28 days) IV ganciclovir 5 mg/kg QD ( adjusted for renal function). A minimum interval of 6 hours is required between the first and second dose.
Placebo
"For first 5 days, dosing of intravenous placebo is daily, given every 12 hours. After first 5 days (up to 28 days), IV placebo QD. A minimum interval of 6 hours is required between the first and second dose.~The placebo is an IV solution that does not contain any active medications."
University of Pittsburgh Medical Center, Pittsburgh
Wakeforest University, School of Medicine, Winston-Salem
Ohio State University Medical Center, Columbus
The Cleveland Clinic Foundation, Cleveland
Northwestern University, Chicago
University of Colorado / National Jewish Health / Swedish Medical Center, Denver
The Oregon Clinic, Portland
Harborview Medical Center, Seattle
University of Washington Medical Center / Harborview Medical Center, Seattle
Baystate Critical Care Medicine / Tufts University School of Medicine, Springfield
University of Michigan, Ann Arbor
University of Pennsylvania Medical Center, Philadelphia
University of Vermont College of Medicine, Burlington
University of Virginia, Charlottesville
Collaborators (1)
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Genentech, Inc.
INDUSTRY
Fred Hutchinson Cancer Center
OTHER