A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 31, 2011

Primary Completion Date

August 31, 2012

Study Completion Date

February 28, 2015

Conditions
Locally Advanced Malignant NeoplasmMalignant Solid Tumour
Interventions
BIOLOGICAL

ALT-836 in combination with gemcitabine

Study participants will receive up to four courses of a 28-day biochemotherapy with the study drug (ALT-836) and gemcitabine. Each treatment course consists of five doses of ALT-836 (on Day 1, 4, 8, 15 and 22) and three doses of gemcitabine (Day 1, 8 and 15). Participants with persistent responses will receive additional two cycles, three doses each, of standard of care gemcitabine therapy.

Trial Locations (4)

14642

University of Rochester Medical Center, James P. Wilmot Cancer Center, Rochester

28203

Carolinas Hematology-Oncology Associates, Charlotte

30322

Emory University, Winship Cancer Institute, Atlanta

52242

University of Iowa Hospitals and Clinics, Iowa City

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Altor BioScience

INDUSTRY

NCT01325558 - A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors | Biotech Hunter | Biotech Hunter