270
Participants
Start Date
September 30, 2011
Primary Completion Date
April 30, 2013
Study Completion Date
April 30, 2013
Proguanil
Proguanil tablets, 1.5mg/kg/day
mefloquine plus artesunate
This treatment is given once a day for 3 days. Patients weighing 5-8 kg receive one paediatric tablet per day, those weighing 9-17 kg two paediatric tablets, those weighing 18-29 kg one adult tablet and those weighing 30 kg and two adult tablets.
Sulfadoxine-pyrimethamine plus amodiaquine
amodiaquine plus sulfadoxine-pyrimethamine supervised at each bimonthly clinic visit (amodiaquine 10mg/kg per day for three days and sulfadoxine-pyrimethamine (25/1.25 mg/kg) on the first day).
Department of Paediatrics and Child Health, University of Ilorin Teaching Hospital, Ilorin
Medical Research Council Unit, The Gambia
OTHER
Wellcome Trust
OTHER
University of Ilorin Teaching Hospital
OTHER
London School of Hygiene and Tropical Medicine
OTHER