Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

PHASE1UnknownINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

August 31, 2016

Study Completion Date

January 31, 2017

Conditions
Breast Cancer
Interventions
DRUG

MM-302 Monotherapy

Escalating doses of MM-302 as a single agent

DRUG

MM-302 in combination with trastuzumab

Escalating MM-302 at an every 4 week dosing schedule, while the dose of trastuzumab is fixed at an every 2 week dosing schedule

DRUG

MM-302 in combination with trastuzumab q3w

Escalating MM-302 at an every 3 week dosing schedule, while the dose of trastuzumab is fixed at an every 3 week dosing schedule

DRUG

MM-302 in combination with trastuzumab and cyclophosphamide

Escalating MM-302 at an every 3 week dosing schedule, while the dose of trastuzumab and cyclophosphamide is fixed at an every 3 week dosing schedule

Trial Locations (5)

Unknown

University of California San Francisco, San Francisco

University of Indiana, Indianapolis

Dana Farber Cancer Center, Boston

Karmanos Cancer Center, Detroit

Washington University, St Louis

Sponsors
All Listed Sponsors
lead

Merrimack Pharmaceuticals

INDUSTRY

NCT01304797 - Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer | Biotech Hunter | Biotech Hunter