NCT01299597View on ClinicalTrials.gov

A Single-centre Open Label Study to Investigate the Effect of Repeat Doses of SB-649868 on the Pharmacokinetics of Simvastatin and Atorvastatin in Healthy Male Volunteers.

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 18, 2010

Primary Completion Date

February 26, 2010

Study Completion Date

February 26, 2010

Conditions
Sleep Disorders
Interventions
DRUG

Atorvastatin

20mg single dose given alone and coadministered with SB649868 on day 8 and 12 of the 14-day repeat dose period.

DRUG

Simvastatin

10mg single dose given alone and coadministered with SB649868 on day 12 and 14 of the 14-day repeat dose period.

DRUG

SB649868

20mg daily given for 14 days.

Trial Locations (1)

14050

GSK Investigational Site, Berlin

Sponsors

Lead Sponsor

GlaxoSmithKline
All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY

NCT01299597 - A Single-centre Open Label Study to Investigate the Effect of Repeat Doses of SB-649868 on the Pharmacokinetics of Simvastatin and Atorvastatin in Healthy Male Volunteers. | Biotech Hunter | Biotech Hunter